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No married or separating men, women, couples or alcoholics. Listing a study does not mean it has been evaluated by the U. The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Actual Enrollment :. I guess you aren't the man I thought you were, Lonely ladies want nsa Milton another guy. Curr Med Res Opin.
Actual Primary Completion Date :. Epub Mar 9. Everolimus in postmenopausal hormone-receptor-positive advanced breast cancer. treatment with exemestane or mTOR inhibitors. How about starting an ltr with a great friendship and all that that brings?
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In the subject of your replyplease put "Your Quote" and tell me about your opinion of it somewhere in your reply.] Study record managers: refer to the Data Element Definitions lsdies submitting registration or information. Everolimus two 5 mg tablets daily were administered in a blinded manner on their respective treatment arms by continuous oral daily dosing. Drug: Everolimus Placebo Placebo was formulated to be indistinguishable from the everolimus tablets.
Matching placebo two tablets daily were administered in a blinded manner on their respective treatment arms by continuous oral daily dosing. If a patient did not progress or known to have died at the date of the analysis cut-off or start of another antineoplastic therapy, the PFS date was censored to the date of last adequate tumor assessment prior to cut-off date or start of antineoplastic therapy. If a patient is not known to have died, survival was censored at the date of last contact.
Scale score ranges:0 to 5, 5 being the worst. Scale index: 0: Fully active, able to carry on all pre-disease performance without restriction. Cannot carry on any self-care. Totally confined to bed or chair. These include 5 functional scales, 3 symptom scales, a global health status - QoL scale, and 6 single items. Each of the multi-item scales includes a different set of items - no item occurs in more than 1 scale. All of the scales measures range in score from 0 to The principle for scoring these scales: 1.
Linear transformation to standardize the raw score, so that scores range from 0 to ; a higher score represents a higher "better" level of functioning, or a higher "worse" level of symptoms.
Patients who did not achieve a confirmed PR or CR were censored at last adequate tumor assessment date when they did not progress. The start date was the date of first documented response CR or PR and lavies end date and censoring is defined the same as that for time to progression.
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